Abstract: Healthcare and crisis management are pervaded by the usage of Information Systems (IS). Virtually all IS rely on data storage. Despite the document-oriented nature of medical datasets, the prevailing kind of database used are relational (RDBMS) ones. In order to find a more adequate solution in a development project for a patientregistry, we evaluated a document-based database incorporated into the data storage layer of a system. To foster the understanding of this technology, we present the background of form-originated data storage in healthcare, introduce document-based databases, and describe our scenario. Based on our findings, we generalize the results with a focus on crisis management. We found that document-based databases such as CouchDB are well-suited for IS in medical contexts and might be a feasible option for the future implementation of systems in various fields of healthcare, crisis response, and medical research. © 2012 ISCRAM.